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Nolvadex is one of the most accessible antiestrogens. It is part of the category of anti-estrogen, selective modulators of estrogen receptors, and has so many estrogenic characteristics agonists and antagonists. Rather, it can act as estrogen in some tissues, and block the action of the hormone mentioned above, among others. In breast tissue is a strong anti estrogen, so it is used for the cure of breast cancer, in women. It is sometimes used up as a method of prevention, being used by women with a history of breast cancer in the family.
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In the case of bodybuilders and sportsmen, tamoxifen citrate is used to attack the side effects of estrogenic nature caused by the use of certain anabolic steroids and androgens.
The main cause of concern among bodybuilders and athletes is gynecomastia, the development of female breast tissue in men. The first signs of gynecomastia are small inflammations below the nipples; if left to evaluate can transform solid tissue and considerable dimensions, which can only be treated surgically
Another unwanted effect of estrogen is the water retention that leads to the covering of muscles and the disappearance of the definition. Fat accumulation may also appear. To prevent all these side effects Nolvadex is used during a diet with steroids that are easily flavored. If the priority is definition, stronger anti-estrogens such as Arimidex are used.
Another ability of Nolvadex is that it helps the growth of follicular stimulation hormone and luteinizing hormone.
In the liver, Nolvadex acts as estrogen, which is fine because it helps the regulation of cholesterol, by promoting good cholesterol (HDL) and reducing bad (LDL). So it is preferable to use Nolvadex during a steroid diet to prevent gynecomastia. But in the case of large doses of steroids, tamoxifen improves serum cholesterol by a few percentages, and can not prevent total cardio vascular effects.
Nolvadex is a hormonal therapy. This medicine is classified as an antiestrogen.
Nolvadex may be given as an adjuvant treatment (treatment after successful surgery) in women or men who have breast cancer with negative or positive lymph nodes
Nolvadex may be prescribed for metastatic breast cancer (cancer that has spread) in both women and men.
Nolvadex may be prescribed for women with ductal carcinoma who have completed surgery and radiation therapy. nolvadex may reduce the risk of invasive breast cancer.
Women who are at high risk of breast cancer may be prescribed nolvadex to reduce the incidence of breast cancer.
Tamoxifen may also be prescribed for the treatment of ovarian cancer.
if they think it might be useful.
Nolvadex is a pill that is taken by mouth. The tablet should be swallowed whole, taken at approximately the same time each day, with a full glass of water. If you miss a dose, do not take a double dose the next day. The amount of nolvadex depends on many factors, including your overall health and your other health problems, and the type of cancer or disease being treated.
Most common side effects:
- Suffocation
- Vaginal secretions
- Swelling (fluid retention in the feet, ankles, or hands).
- Loss of libido (especially in men)
Less frequent:
- Sickness
- Menstrual Irregularities
- Vaginal bleeding
- Weightloss
- Humor changes
- Visual disturbances
Before starting treatment with nolvadex, tell your doctor about any other medicines you take (including prescription drugs, over-the-counter medicines, vitamins, herbal remedies, etc.). Do not take aspirin or aspirin-containing products unless your doctor specifically allows it. Tell your doctor if you ever had a blood clot that required medical treatment. If you are pregnant or think you may be pregnant, tell your doctor before starting treatment. nolvadex is a drug classified as high risk for it. Women who are pregnant or who become pregnant during treatment should be informed about the possible risk to the fetus. For both men and women: Avoid conception while taking nolvadex. Barrier contraceptive methods, such as condoms, are recommended. Consult your doctor when you can safely conceive the baby after treatment. Do not breast-feed while you are receiving this medicine.
Tips:
Do not stop these medicines unless told to do so by your doctor. Treatment can last up to 5 years
If you experience hot flashes, wear light clothing, maintain a cool environment and put cool cloths on your head may reduce symptoms. If symptoms worsen or become intolerable, consult a physician.
You may feel nauseous when using this medicine. If you experience nausea, take anti-emetic medicines prescribed by your doctor and often eat small portions of food. It also helps to suck pills and chew gum.
Avoid sun exposure. Use sunscreen with a protective factor of 15 or higher and protective clothing.
You must minimize or completely avoid the consumption of alcoholic beverages. You should talk about this with your doctor.
Get plenty of rest.
Maintain good nutrition.
Control and testing:
Your doctor will test you regularly during treatment with tamoxifen, to monitor side effects and check your response to treatment. Your doctor may order periodic complete blood counts as well as other blood tests to monitor the functioning of other organs.
Women should have a gynecological examination before and during therapy, periodically.
The use of hormone therapy to treat cancer is based on the observation that on the surface of some tumor cells there are specific hormone receptors necessary for cell growth. Hormone therapy may work by stopping the production of a particular hormone, nolvadex is an antiestrogen. Antiestrogens bind to the estrogen receptor site in cancer cells, blocking the passage of estrogen into the cancer cell. This interferes with cell growth and eventually causes cell death.
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